Made in Vancouver  •  Compounded fresh on Main Street  •  Shipping Canada-wide
Prescription skincare* · Built by you · Approved by doctors

Your skin.
Your formula.
One prescription.

Start with tretinoin, the most studied prescription ingredient in dermatology. Add the boosters your skin actually needs. A pharmacist checks your blend, a doctor approves it, and we compound it fresh at our pharmacy on Main Street.

✓ Doctor approved ✓ Pharmacist checked ✓ Compounded fresh ✓ Free shipping ✓ Cancel anytime

Honest pricing, live as you build: from $49/month all-in. Every ingredient priced on its card.

Woman holding her personalized SkinOnMain formula bottle
Rx BaseTretinoin 0.025%
Your boostersNiacinamide + Vit C + HA
One Rx active Boosters chosen by you Checked by pharmacists Approved by doctors Compounded on Main St Shipped Canada-wide One Rx active Boosters chosen by you Checked by pharmacists Approved by doctors Compounded on Main St Shipped Canada-wide
How it works

From your bathroom mirror to your mailbox, in days.

01
~5 minutes

Build your formula

Pick your tretinoin base, then add the boosters that match your goals. We explain what each one does and which combinations make sense. Or keep it plain and simple.

02
Same day

Pharmacist check

A compounding pharmacist reviews your blend for compatibility, concentration, and stability, and fine-tunes it if needed. Real expertise, not an algorithm.

03
1-2 business days

Doctor approval

A licensed Canadian prescriber reviews your intake, photos, and medical history, and issues your prescription if it is right for you. No waiting rooms.

04
3-5 business days

Made fresh & shipped

Your formula is compounded fresh at our pharmacy on Main Street, Vancouver, then shipped free anywhere in Canada. Refills arrive monthly, automatically.

The Formula Bar™

Nobody else lets you build your own prescription skincare.

One Rx active. Unlimited personality.
Tretinoin does the heavy lifting. Your boosters handle brightening, calming, hydration, and barrier support.
Honest ingredient education. Honest ingredient pricing.
We tell you what pairs beautifully, what is pointless, and what we will not put in the same bottle. Every ingredient shows its price, and your total builds live. No surprises at checkout.
Humans have the final word.
Every blend is reviewed by an expert compounding pharmacist and approved by a licensed prescriber before it is made.
Open the Formula Bar →
Live preview · Your formula
Tretinoin 0.025% · all-in base $49Rx Base
Niacinamide 4% · +$4Added
THD Vitamin C 2% · +$9Added
Hyaluronic Acid 1% · +$5Added
Alpha Arbutin · +$7Available
Peptide Menu · from +$10Available
Your total, live
$67/month
Customize →
Macro of a silky compounded cream swirl in tangerine and violet light
The base · Prescription only

Tretinoin: the gold standard, not the latest trend.

Tretinoin has been studied for over 50 years and is approved in Canada for acne. Prescribers may also use it off-label for the appearance of fine lines, texture, and tone. It is the ingredient dermatology keeps coming back to, and you will not find it on a store shelf.

50+years of clinical study
1prescription active per formula
0guesswork with our team behind you
Start with tretinoin →

*Tretinoin is approved in Canada for the treatment of acne. Use for cosmetic purposes is off-label and is determined on an individual basis by a licensed prescriber. Compounded preparations do not have a DIN. All references to skin benefits relate to cosmetic appearance only. Results vary.

The booster library

Know exactly what goes in the bottle, and why.

Every booster is optional, every booster is explained, and the price never changes. Our pharmacists cap formulas at three boosters, because more is not better. Better is better.

Niacinamide

4% · Vitamin B3

Supports the skin barrier and helps the look of enlarged pores and uneven tone.

✓ Great with tretinoin: calms the adjustment phase

THD Vitamin C

2% · Stabilized ester

An oil-soluble vitamin C that brightens the look of dull skin without the sting of ascorbic acid.

✓ Great with tretinoin: brightening partner

Hyaluronic Acid

1% · Humectant

Draws water into the skin for a plumper, more hydrated look while you adjust to tretinoin.

✓ Great with tretinoin: hydration buffer

Alpha Arbutin

2% · Tone specialist

A gentle brightener for the look of dark spots and post-blemish marks.

✓ Pairs well: tone-evening duo with vitamin C

Peptide Complex

3% · Matrixyl-type

Signal peptides that support the look of firmer, bouncier skin over time.

✓ Plays nicely with everything

Ferulic Acid

0.5% · Antioxidant

A plant antioxidant that helps stabilize vitamin C and defends against daily environmental stress.

◐ Best when paired with vitamin C

Bisabolol

0.5% · From chamomile

A soothing agent that helps calm the look of redness, especially in the first weeks.

✓ Great for sensitive starts

Ceramide Complex

2% · Barrier lipids

Skin-identical lipids that reinforce your moisture barrier while tretinoin does its work.

✓ Great with tretinoin: barrier bodyguard

What we will not add: exfoliating acids (AHA/BHA), benzoyl peroxide, or fragrance in the same bottle as tretinoin. Some things are better in separate products, and we will tell you when that is the case. Final formulas are always at the discretion of the pharmacist and prescriber.

Radically transparent pricing

Every ingredient priced. Every price printed right here.

Others hide their pricing behind a questionnaire. We put a price tag on every ingredient card and let your total build live, before you share a single detail.

SkinOnMain
from $49/month
  • All-in base: consult, compounding & shipping included
  • Boosters from $4/month, priced on every card
  • Peptide menu: pick and price each peptide
  • Pharmacist review of every blend
  • Doctor consultation & prescription review
  • Compounded fresh, every month
  • Pause or cancel whenever you like
$???
  • Price revealed only after your intake
  • Pre-set formulas, no input from you
  • No pharmacist you can actually visit
  • No idea what any ingredient costs
  • Support ticket queues

The typical telehealth skincare experience in Canada today.

Pharmacist compounding a formula at the marble bench
A real pharmacy. A real street.

Made by humans, on Main Street.

SkinOnMain is not a faceless app. Every formula is compounded at CareBridge Pharmacy on Main Street in Vancouver by licensed compounding pharmacists. Walk in and say hi, watch where your skincare is made, or just enjoy knowing that a real person you could shake hands with checked your formula.

CompoundingCareBridge Pharmacy, Main St, Vancouver
PrescribersLicensed Canadian physicians & NPs
DeliveryCanada-wide, free, tracked
More from the Bar

Skin first. Then everything else.

FAQ

Questions? Good. Curious skin is healthy skin.

Do I really get to design my own formula?

Yes, within safe, sensible limits. You choose your boosters from our library and tell us your goals. A compounding pharmacist reviews every blend for compatibility and concentration, and a licensed prescriber makes the final call on the prescription base. If something in your mix is not a good idea, we will explain why and suggest a better path, never just silently swap it.

Do I need to see my own doctor first?

No. Our partnered licensed Canadian prescribers review your online intake, photos, and health history. If a prescription is appropriate, it is issued online, and your formula goes straight to compounding. No referrals, no waiting rooms.

How does the pricing work?

Your base price (from $49/month) is all-in: it covers the doctor consultation, pharmacist review, monthly fresh compounding, and free shipping anywhere in Canada. Each booster then adds its real price, shown right on its card, from $4/month. Peptides are priced individually on the peptide menu. Your total builds live as you build your formula, so the number you see at the Formula Bar is the number you pay. No fees appear at checkout, ever.

Is tretinoin safe?

Tretinoin is a prescription medication with over 50 years of study. Most people experience an adjustment phase with mild dryness, redness, or peeling. It is not suitable during pregnancy or breastfeeding, and daily sunscreen is a must. Your prescriber reviews your health history to confirm it is appropriate for you, and our team supports you through the adjustment weeks.

Tretinoin is approved in Canada for acne. Cosmetic use is off-label and at your prescriber's discretion. Compounded formulas do not have a DIN.

How fast will I get my formula?

Intake takes about five minutes. Prescriber review is typically one to two business days. Compounding and shipping take another three to five business days. Most patients have their formula in hand within a week of getting started.

Can I change my formula later?

Yes, and you should. Skin changes with seasons, stress, and time. You can adjust your boosters before any refill, and your pharmacist can suggest tweaks based on how your skin is responding. Your prescription base can be adjusted at your prescriber's discretion.

No waiting rooms · No guesswork · No hidden prices

Ready to build something your skin will thank you for?

Five minutes at the Formula Bar. A pharmacist and a doctor in your corner. A fresh formula at your door.

Build My Formula →